All You Need to Know about Premenstrual Syndrome! Premenstrual syndrome, PMS in short is a medical condition that affects a woman’s emotions. Symptoms include backache, weight gain, watery eyes, anxiety, depression, headache, irritation and breast tenderness. It occurs just before or a few days before the menstrual cycle. Reason of premenstrual syndrome is unknown but it is said that misbalance in hormones such as progesterone and estrogen can be a possible reason behind the occurrence of PMS. There is no specific treatment and prevention method till date. Symptoms can be treated by maintaining a healthy lifestyle, which includes regular exercise and proper diet. Some drugs such as Aspirin, Naproxen, Ibuprofen etc., are given to overcome physical symptoms like headache or backache.